GPR18

Across TCGA patient cohorts, GPR18 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,567 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible GPR18-associated proteins across cancer lineages are AKNA_S316, ABI3, and RASSF2. Each is linked with GPR18 in more than 4 cancer types. Because this analysis shows association rather than direction, both GPR18-to-partner and partner-to-GPR18 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GPR18 versus AKNA_S316 in OV, with a Pearson correlation of 0.54.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR18→partner) and Y-score (partner→GPR18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	AKNA_S316 →	+0.557	+0.687	<.001	.005	3	5
OV	ABI3 →	+0.488	+0.729	<.001	<.001	3	5
OV	RASSF2 →	+0.516	+0.707	<.001	<.001	3	5
COAD	SEPTIN6 →	+0.482	+0.643	<.001	<.001	3	5
PDAC	LSP1_S252 →	+0.697	+0.314	<.001	.001	3	5
OV	ADA2 →	+0.524	+0.642	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,567 associations by consensus.

GPR18 vs AKNA_S316 — OV

Explore this scatter interactively →