GPR179

Across TCGA cell cohorts, GPR179 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,158 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible GPR179-associated GO terms across cancer lineages are Negative regulation of ubiquitin-dependent protein catabolic process, Regulation of proteasomal protein catabolic process, and RNA catabolic process. Each is linked with GPR179 in more than 12 cancer types. Because this analysis shows association rather than direction, both GPR179-to-partner and partner-to-GPR179 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of ubiquitin-dependent protein catabolic process grouped by GPR179-low versus GPR179-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR179→partner) and Y-score (partner→GPR179) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Negative regulation of ubiquitin-dependent protein catabolic process →	+0.079	+0.152	<.001	.004	3	13
OESOPHAGUS	Regulation of proteasomal protein catabolic process →	+0.079	+0.162	<.001	<.001	3	11
PANCREAS	RNA catabolic process →	+0.070	+0.108	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Response to starvation →	+0.067	+0.119	<.001	<.001	3	11
LUNG_SCLC	Cytoskeleton-dependent intracellular transport →	+0.049	+0.504	.003	.009	3	11
OESOPHAGUS	Negative regulation of proteasomal ubiquitin-dependent protein catabolic process →	+0.081	+0.206	.003	<.001	2	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,158 associations by consensus.

Negative regulation of ubiquitin-dependent protein catabolic process by GPR179 expression — OESOPHAGUS

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