GPR179

Across TCGA pan-cancer cohorts, GPR179 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated GPR179 data layer compared with 10 for mutation status.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher GPR179 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated GPR179 expression acts as an unfavorable survival marker, although some lineages such as LUAD and LGG show a favorable association.

KIRP, UCEC, and COAD are the cancer types where GPR179 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	DFS	Median	All	0.848	0.957	<.001	129	view →
UCEC	OS	Tertile	All	0.534	0.831	.002	60	view →
COAD	OS	Quartile	All	0.545	0.716	.001	59	view →
LUAD	OS	Median	All	0.857	0.711	.002	49	view →
LGG	DFS	Median	All	0.798	0.674	<.001	34	view →
BLCA	OS	Quartile	IV	0.705	0.449	.009	32	view →
ACC	DFS	Median	All	0.514	0.778	.001	32	view →
KIRC	DFS	Median	All	0.761	0.848	.007	31	view →
STAD	DFS	Median	III,IV	0.591	0.305	.015	20	view →
UVM	DFS	Tertile	All	0.258	0.638	.013	20	view →
THCA	OS	Median	All	0.965	1.000	.026	14	view →
CHOL	DFS	Median	II,III,IV	0.121	0.626	.002	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

GPR179–KIRP (DFS)

Open the KIRP breakdown →