GPR176

Across TCGA patient cohorts, GPR176 RNA expression is significantly associated with the RNA expression of many other genes, with 19,000 significant associations in total. THYM shows the largest number of these associations.

The most reproducible GPR176-associated genes across cancer lineages are FBN1, NUAK1, and KIRREL1. Each is linked with GPR176 in more than 32 cancer types. Because this analysis shows association rather than direction, both GPR176-to-partner and partner-to-GPR176 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GPR176 versus FBN1 in BLCA, with a Pearson correlation of 0.68.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR176→partner) and Y-score (partner→GPR176) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	FBN1 →	+2.021	+1.550	<.001	<.001	3	33
CHOL	NUAK1 →	+1.334	+1.834	.001	.003	3	33
THYM	KIRREL1 →	+2.342	+1.657	<.001	<.001	3	31
DLBC	LRRC8C →	+1.119	+0.963	<.001	<.001	3	31
UVM	HIVEP2 →	+1.153	+1.735	<.001	<.001	3	31
CHOL	RAB23 →	+1.256	+2.189	<.001	<.001	3	31

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,000 associations by consensus.

GPR176 vs FBN1 — BLCA

Explore this scatter interactively →