GPR176

Across TCGA patient cohorts, GPR176 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,018 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible GPR176-associated proteins across cancer lineages are RASA3, VCL_S346, and CALD1. Each is linked with GPR176 in more than 7 cancer types. Because this analysis shows association rather than direction, both GPR176-to-partner and partner-to-GPR176 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GPR176 versus RASA3 in OV, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR176→partner) and Y-score (partner→GPR176) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	RASA3 →	+0.552	+0.886	<.001	<.001	3	8
BRCA	VCL_S346 →	+0.637	+0.723	<.001	<.001	3	8
UCEC	CALD1 →	+0.819	+0.626	<.001	<.001	3	8
OV	AEBP1 →	+0.791	+0.887	<.001	<.001	3	8
OV	CLIC4 →	+0.599	+1.294	<.001	<.001	3	8
OV	CNN3 →	+0.831	+1.163	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,018 associations by consensus.

GPR176 vs RASA3 — OV

Explore this scatter interactively →