GPR174

Across TCGA patient cohorts, GPR174 RNA expression is significantly associated with the RNA expression of many other genes, with 18,368 significant associations in total. DLBC shows the largest number of these associations.

The most reproducible GPR174-associated genes across cancer lineages are SLAMF6, TRAT1, and PYHIN1. Each is linked with GPR174 in more than 33 cancer types. Because this analysis shows association rather than direction, both GPR174-to-partner and partner-to-GPR174 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GPR174 versus SLAMF6 in SKCM, with a Pearson correlation of 0.87.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR174→partner) and Y-score (partner→GPR174) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	SLAMF6 →	+2.618	+1.872	<.001	<.001	3	34
THYM	TRAT1 →	+2.103	+1.335	<.001	<.001	3	34
SKCM	PYHIN1 →	+1.823	+1.661	<.001	<.001	3	34
SKCM	GPR171 →	+1.949	+1.836	<.001	<.001	3	34
SKCM	SLA2 →	+2.054	+1.755	<.001	<.001	3	34
SKCM	CD2 →	+2.983	+1.807	<.001	<.001	3	34

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,368 associations by consensus.

GPR174 vs SLAMF6 — SKCM

Explore this scatter interactively →