Across TCGA patient cohorts, GPR173 mutation is significantly associated with the RNA expression of many other genes, with 2,070 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GPR173-associated genes across cancer lineages are H2BC17, LINC00869, and H2BP8. Each is linked with GPR173 in more than 1 cancer types. Because this analysis shows association rather than direction, both GPR173-to-partner and partner-to-GPR173 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR173→partner) and Y-score (partner→GPR173) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	H2BC17 →	+0.680	+2.081	.003	.001	3	2
UCEC	LINC00869 →	-0.524	-2.560	<.001	.001	3	2
COAD	H2BP8 →	+0.069	+3.917	.002	.009	3	2
COAD	MAP1LC3P →	+0.447	+2.830	<.001	.003	3	2
CESC	TRGV11 →	+0.072	+3.411	.004	.009	3	2
LUSC	CTBP2P5 →	+0.059	+4.884	.006	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,070 associations by consensus.

Exploration

GPR173 survival (RNA) · tumor vs normal (RNA) · all GPR173 data types