Across TCGA pan-cancer cohorts, GPR160P1 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of GPR160P1’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where GPR160P1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types GPR160P1 is over-expressed in tumor, although a few such as BRCA show the opposite, repressed pattern.
KIRC, BRCA, and ESCA are the cancer types where GPR160P1 tumor–normal differential expression is most reproducible.