GPR160

Across TCGA patient cohorts, GPR160 mutation is significantly associated with the total protein of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GPR160-associated genes across cancer lineages are Gab2, JNK_pT183_Y185, and P-Cadherin. Each is linked with GPR160 in more than 1 cancer types. Because this analysis shows association rather than direction, both GPR160-to-partner and partner-to-GPR160 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Gab2 grouped by GPR160-low versus GPR160-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR160→partner) and Y-score (partner→GPR160) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Gab2 →	+0.581	+3.321	.001	.010	3	1
UCEC	JNK_pT183_Y185 →	-0.188	-3.000	.033	.036	3	1
UCEC	P-Cadherin →	-0.179	-2.990	.017	.036	3	1
UCEC	Tuberin →	+0.443	+3.321	.001	.010	2	1
UCEC	p62 Lck ligand →	+0.476	+3.321	.005	.010	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Gab2 by GPR160 expression — UCEC

Explore this box plot interactively →