GPR156

Across TCGA cell cohorts, GPR156 mutation is significantly associated with the RNA expression of many other genes, with 183 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GPR156-associated genes across cancer lineages are KRTAP4-4, TCF21, and SFT2D3. Each is linked with GPR156 in more than 1 cancer types. Because this analysis shows association rather than direction, both GPR156-to-partner and partner-to-GPR156 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRTAP4-4 grouped by GPR156-low versus GPR156-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR156→partner) and Y-score (partner→GPR156) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	KRTAP4-4 →	+0.030	+4.807	<.001	.006	3	1
BLOOD_Leukemia	TCF21 →	+0.015	+3.705	<.001	.007	3	1
BLOOD_Leukemia	SFT2D3 →	+0.748	+4.450	<.001	.001	3	1
BLOOD_Leukemia	OR10R2 →	+1.412	+3.551	<.001	.009	3	1
OVARY	ODF4 →	+0.035	+5.196	<.001	.005	3	1
OVARY	GLT6D1 →	+0.409	+5.196	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 183 associations by consensus.

KRTAP4-4 by GPR156 expression — BLOOD_Myeloma

Explore this box plot interactively →