GPR155

Across TCGA patient cohorts, GPR155 mutation is significantly associated with the RNA expression of many other genes, with 3,377 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GPR155-associated genes across cancer lineages are MIR507, SAPCD2P1, and SNRPBP1. Each is linked with GPR155 in more than 1 cancer types. Because this analysis shows association rather than direction, both GPR155-to-partner and partner-to-GPR155 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR507 grouped by GPR155-low versus GPR155-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR155→partner) and Y-score (partner→GPR155) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MIR507 →	+0.352	+5.178	<.001	.002	3	2
HNSC	SAPCD2P1 →	+0.042	+3.881	.001	.006	3	2
HNSC	SNRPBP1 →	+0.242	+4.200	<.001	.004	3	2
HNSC	HMGN1P32 →	+0.189	+4.548	<.001	.001	3	2
HNSC	RN7SL284P →	+0.182	+3.780	<.001	.007	3	2
KIRP	RNASEH2CP1 →	+0.067	+4.497	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,377 associations by consensus.

MIR507 by GPR155 expression — HNSC

Explore this box plot interactively →