GPR155

Across TCGA cell cohorts, GPR155 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GPR155-associated genes across cancer lineages are GAGE12E, GIMAP7, and PRR30. Each is linked with GPR155 in more than 1 cancer types. Because this analysis shows association rather than direction, both GPR155-to-partner and partner-to-GPR155 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GAGE12E grouped by GPR155-low versus GPR155-high in LUNG_NSCLC_LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR155→partner) and Y-score (partner→GPR155) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	GAGE12E →	+0.076	+4.643	<.001	.008	3	1
CNS	GIMAP7 →	+0.044	+4.169	<.001	.008	3	1
CNS	PRR30 →	+0.015	+4.643	<.001	.003	3	1
CNS	OR10D3 →	+0.016	+4.321	.002	.009	3	1
CNS	FBXO47 →	+0.015	+4.315	<.001	.006	3	1
BLOOD_Leukemia	PRAMEF7 →	+0.019	+5.124	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

GAGE12E by GPR155 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →