GPR152

Across TCGA patient cohorts, GPR152 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,881 significant associations in total. STAD shows the largest number of these associations.

The most reproducible GPR152-associated GO terms across cancer lineages are Organelle fusion, Protein polyubiquitination, and Regulation of Ras protein signal transduction. Each is linked with GPR152 in more than 25 cancer types. Because this analysis shows association rather than direction, both GPR152-to-partner and partner-to-GPR152 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Organelle fusion grouped by GPR152-low versus GPR152-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR152→partner) and Y-score (partner→GPR152) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Organelle fusion →	+0.060	+0.201	<.001	<.001	3	26
STAD	Protein polyubiquitination →	+0.062	+0.147	<.001	<.001	3	26
STAD	Regulation of Ras protein signal transduction →	+0.061	+0.160	<.001	<.001	3	26
STAD	Epigenetic regulation of gene expression →	+0.066	+0.149	<.001	<.001	3	25
STAD	Nuclear export →	+0.066	+0.140	<.001	<.001	3	25
SCLC	Protein polymerization →	+0.070	+0.971	<.001	<.001	2	26

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,881 associations by consensus.

Organelle fusion by GPR152 expression — ESCA

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