GPR152

Across TCGA cell cohorts, GPR152 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,637 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GPR152-associated GO terms across cancer lineages are Regulation of transcription initiation by RNA polymerase II, Regulation of DNA-templated transcription initiation, and Regulation of syncytium formation by plasma membrane fusion. Each is linked with GPR152 in more than 7 cancer types. Because this analysis shows association rather than direction, both GPR152-to-partner and partner-to-GPR152 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of transcription initiation by RNA polymerase II grouped by GPR152-low versus GPR152-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR152→partner) and Y-score (partner→GPR152) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Regulation of transcription initiation by RNA polymerase II →	+0.046	+0.031	<.001	<.001	3	8
LIVER	Regulation of DNA-templated transcription initiation →	+0.072	+0.034	<.001	.004	3	7
OVARY	Regulation of syncytium formation by plasma membrane fusion →	+0.069	+0.025	.001	.003	3	7
LIVER	Positive regulation of DNA-templated transcription initiation →	+0.072	+0.034	.001	.003	3	6
LIVER	Positive regulation of transcription initiation by RNA polymerase II →	+0.071	+0.034	.001	.004	3	6
OESOPHAGUS	Circadian regulation of gene expression →	+0.056	+0.032	<.001	.004	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,637 associations by consensus.

Regulation of transcription initiation by RNA polymerase II by GPR152 expression — CNS

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