GPR151

Across TCGA patient cohorts, GPR151 mutation is significantly associated with the RNA expression of many other genes, with 464 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GPR151-associated genes across cancer lineages are MIR6783, KRTAP21-1, and CIDECP1. Each is linked with GPR151 in more than 3 cancer types. Because this analysis shows association rather than direction, both GPR151-to-partner and partner-to-GPR151 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6783 grouped by GPR151-low versus GPR151-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR151→partner) and Y-score (partner→GPR151) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR6783 →	+0.548	+2.294	.002	.006	3	4
BRCA	KRTAP21-1 →	+0.143	+5.148	<.001	.008	3	3
UCEC	CIDECP1 →	+0.630	+3.638	<.001	.001	3	2
UCEC	FAM53B →	+0.672	+3.595	<.001	.001	3	2
UCEC	RN7SKP230 →	+0.297	+2.704	.007	.001	3	2
BLCA	AP1B1P2 →	+1.241	+3.971	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 464 associations by consensus.

MIR6783 by GPR151 expression — UCEC

Explore this box plot interactively →