GPR143

Across TCGA patient cohorts, GPR143 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,024 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GPR143-associated proteins across cancer lineages are SHROOM2, SHROOM2_S1297, and SHROOM2_S313. Each is linked with GPR143 in more than 8 cancer types. Because this analysis shows association rather than direction, both GPR143-to-partner and partner-to-GPR143 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GPR143 versus SHROOM2 in COAD, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR143→partner) and Y-score (partner→GPR143) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	SHROOM2 →	+0.922	+2.051	.002	<.001	3	9
COAD	SHROOM2_S1297 →	+0.561	+1.443	<.001	<.001	3	7
COAD	SHROOM2_S313 →	+0.561	+1.721	<.001	<.001	3	7
COAD	SHROOM2_S779 →	+0.959	+1.891	<.001	<.001	3	7
LSCC	SHROOM2_S413 →	+0.767	+0.891	<.001	<.001	3	6
LSCC	SHROOM2_S422 →	+1.068	+1.155	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,024 associations by consensus.

GPR143 vs SHROOM2 — COAD

Explore this scatter interactively →