GPR143

Across TCGA cell cohorts, GPR143 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,707 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible GPR143-associated GO terms across cancer lineages are Pigment metabolic process involved in pigmentation, Microtubule bundle formation, and Sensory perception of light stimulus. Each is linked with GPR143 in more than 13 cancer types. Because this analysis shows association rather than direction, both GPR143-to-partner and partner-to-GPR143 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Pigment metabolic process involved in pigmentation grouped by GPR143-low versus GPR143-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR143→partner) and Y-score (partner→GPR143) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Pigment metabolic process involved in pigmentation →	-0.405	-2.013	<.001	.001	3	14
LARGE_INTESTINE	Microtubule bundle formation →	-0.043	-1.062	<.001	<.001	3	11
BONE	Sensory perception of light stimulus →	-0.052	-0.195	.002	.007	2	9
PANCREAS	Regulation of syncytium formation by plasma membrane fusion →	+0.110	+1.299	<.001	.002	3	7
PANCREAS	Post-translational protein targeting to endoplasmic reticulum membrane →	+0.098	+1.073	<.001	.003	3	7
CNS	Visual perception →	-0.051	-0.340	<.001	<.001	1	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,707 associations by consensus.

Pigment metabolic process involved in pigmentation by GPR143 expression — LIVER

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