GPR137B

Across TCGA patient cohorts, GPR137B mutation is significantly associated with the RNA expression of many other genes, with 2,862 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GPR137B-associated genes across cancer lineages are RNU1-17P, TCP11X3P, and RNU6-1226P. Each is linked with GPR137B in more than 2 cancer types. Because this analysis shows association rather than direction, both GPR137B-to-partner and partner-to-GPR137B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU1-17P grouped by GPR137B-low versus GPR137B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR137B→partner) and Y-score (partner→GPR137B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU1-17P →	+0.257	+2.820	<.001	<.001	3	3
UCEC	TCP11X3P →	+0.243	+2.047	<.001	.002	3	3
SKCM	RNU6-1226P →	+0.804	+4.215	<.001	.009	3	2
LIHC	LINC01069 →	+0.118	+5.544	<.001	.004	3	2
LIHC	RN7SL149P →	+0.161	+5.447	<.001	.005	3	2
UCEC	IL21 →	+0.125	+1.874	.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,862 associations by consensus.

RNU1-17P by GPR137B expression — UCEC

Explore this box plot interactively →