GPR137B

Across TCGA cell cohorts, GPR137B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,246 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible GPR137B-associated GO terms across cancer lineages are Proton motive force-driven mitochondrial ATP synthesis, Oxidative phosphorylation, and Aerobic electron transport chain. Each is linked with GPR137B in more than 11 cancer types. Because this analysis shows association rather than direction, both GPR137B-to-partner and partner-to-GPR137B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Proton motive force-driven mitochondrial ATP synthesis grouped by GPR137B-low versus GPR137B-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR137B→partner) and Y-score (partner→GPR137B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Proton motive force-driven mitochondrial ATP synthesis →	+0.125	+1.583	.007	<.001	3	12
OESOPHAGUS	Oxidative phosphorylation →	+0.110	+1.235	<.001	.001	3	12
OESOPHAGUS	Aerobic electron transport chain →	+0.110	+1.115	<.001	<.001	3	11
OESOPHAGUS	Mitochondrial electron transport, NADH to ubiquinone →	+0.094	+1.250	.007	.001	3	11
LARGE_INTESTINE	Vesicle targeting, to, from or within Golgi →	+0.084	+0.857	<.001	.003	3	11
OESOPHAGUS	Proton motive force-driven ATP synthesis →	+0.130	+1.583	.006	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,246 associations by consensus.

Proton motive force-driven mitochondrial ATP synthesis by GPR137B expression — OESOPHAGUS

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