GPR137B

Across TCGA cell cohorts, GPR137B mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible GPR137B-associated genes across cancer lineages are OR10W1, FGF23, and EFCAB3. Each is linked with GPR137B in more than 1 cancer types. Because this analysis shows association rather than direction, both GPR137B-to-partner and partner-to-GPR137B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10W1 grouped by GPR137B-low versus GPR137B-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR137B→partner) and Y-score (partner→GPR137B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	OR10W1 →	+0.019	+4.977	<.001	.007	3	1
LUNG_NSCLC_LUAD	FGF23 →	+0.133	+4.786	<.001	<.001	3	1
LUNG_NSCLC_LUAD	EFCAB3 →	+0.327	+4.343	<.001	.002	3	1
LUNG_NSCLC_LUAD	C16orf82 →	+0.007	+4.078	<.001	.009	3	1
SKIN	OR10H5 →	+0.012	+4.977	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

OR10W1 by GPR137B expression — LARGE_INTESTINE

Explore this box plot interactively →