GPR135

Across TCGA cell cohorts, GPR135 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,123 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GPR135-associated GO terms across cancer lineages are Regulation of cilium assembly, Microtubule polymerization, and Nucleic acid transport. Each is linked with GPR135 in more than 16 cancer types. Because this analysis shows association rather than direction, both GPR135-to-partner and partner-to-GPR135 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of cilium assembly grouped by GPR135-low versus GPR135-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR135→partner) and Y-score (partner→GPR135) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Regulation of cilium assembly →	+0.065	+0.707	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Microtubule polymerization →	+0.111	+0.857	<.001	<.001	3	15
OESOPHAGUS	Nucleic acid transport →	+0.095	+0.684	<.001	<.001	3	15
OESOPHAGUS	RNA transport →	+0.095	+0.684	<.001	<.001	3	15
SOFT_TISSUE	Protein polymerization →	+0.066	+0.750	<.001	<.001	3	15
OESOPHAGUS	RNA export from nucleus →	+0.126	+0.727	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,123 associations by consensus.

Regulation of cilium assembly by GPR135 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →