GPR119

Across TCGA patient cohorts, GPR119 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,840 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GPR119-associated GO terms across cancer lineages are Positive regulation of neuron projection development, RNA 3'-end processing, and Golgi vesicle transport. Each is linked with GPR119 in more than 10 cancer types. Because this analysis shows association rather than direction, both GPR119-to-partner and partner-to-GPR119 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of neuron projection development grouped by GPR119-low versus GPR119-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR119→partner) and Y-score (partner→GPR119) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of neuron projection development →	+0.038	+0.188	<.001	.001	3	9
KIRC	RNA 3'-end processing →	+0.030	+0.018	<.001	.001	2	10
ESCA	Golgi vesicle transport →	+0.051	+0.205	<.001	.009	1	11
UCEC	Transcription initiation at RNA polymerase II promoter →	+0.030	+0.057	<.001	.002	3	8
STAD	Dendrite development →	+0.046	+0.282	<.001	<.001	3	8
UCEC	Positive regulation of DNA-templated transcription, elongation →	+0.033	+0.032	<.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,840 associations by consensus.

Positive regulation of neuron projection development by GPR119 expression — STAD

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