GPR101

Across TCGA cell cohorts, GPR101 mutation is significantly associated with the RNA expression of many other genes, with 340 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GPR101-associated genes across cancer lineages are WDR87, ELOA3DP, and IQCF6. Each is linked with GPR101 in more than 1 cancer types. Because this analysis shows association rather than direction, both GPR101-to-partner and partner-to-GPR101 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, WDR87 grouped by GPR101-low versus GPR101-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR101→partner) and Y-score (partner→GPR101) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	WDR87 →	+0.013	+2.675	.004	.003	3	2
LARGE_INTESTINE	ELOA3DP →	+0.019	+2.425	<.001	.004	3	2
LARGE_INTESTINE	IQCF6 →	+0.143	+2.619	.001	.002	3	2
LUNG_NSCLC_LUAD	OR7G2 →	+0.018	+4.887	<.001	.009	3	1
LUNG_NSCLC_LUAD	KRTAP21-1 →	+0.033	+6.266	<.001	<.001	3	1
LUNG_NSCLC_LUAD	CXorf51A →	+0.076	+4.887	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 340 associations by consensus.

WDR87 by GPR101 expression — LARGE_INTESTINE

Explore this box plot interactively →