GPR1-AS

Across TCGA pan-cancer cohorts, GPR1-AS RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated GPR1-AS data layer.

The strongest signal is observed in thymoma (THYM), where higher GPR1-AS RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated GPR1-AS expression acts as an unfavorable survival marker, although some lineages such as HNSC and UCS show a favorable association.

THYM, KICH, and KIRC are the cancer types where GPR1-AS RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THYM	DFS	Tertile	All	0.705	0.934	<.001	102	view →
KICH	DFS	Tertile	All	0.715	0.963	.001	93	view →
KIRC	DFS	Tertile	All	0.497	0.678	<.001	89	view →
HNSC	DFS	Quartile	All	0.748	0.617	.009	34	view →
LGG	DFS	Tertile	All	0.652	0.772	.003	32	view →
BRCA	DFS	Quartile	II,III,IV	0.912	0.951	.001	31	view →
UCS	DFS	Median	All	0.660	0.384	.004	30	view →
BLCA	OS	Quartile	III,IV	0.744	0.608	.020	28	view →
OV	OS	Quartile	All	0.762	0.876	.001	22	view →
PAAD	OS	Tertile	All	0.516	0.640	.032	21	view →
CHOL	OS	Quartile	All	0.089	0.676	.001	19	view →
SKCM	OS	Tertile	IV	0.234	0.706	.034	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

GPR1-AS–THYM (DFS)

Open the THYM breakdown →