GPR1-AS

Across TCGA pan-cancer cohorts, GPR1-AS RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of GPR1-AS’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where GPR1-AS RNA is repressed in tumor relative to normal tissue. In most cancer types GPR1-AS is over-expressed in tumor, although a few such as KIRC and COAD show the opposite, repressed pattern.

KIRC, HNSC, and COAD are the cancer types where GPR1-AS tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in GPR1-AS RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	II,III,IV	−0.015	.014	6	view →
HNSC	All	All	+0.128	.006	4	view →
COAD	All	II,III,IV	−0.006	.027	4	view →
THCA	All	III,IV	+0.013	.011	2	view →
BLCA	Male	IV	−0.062	.029	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

GPR1-AS–KIRC

Open the KIRC breakdown →