GPN3

Across TCGA patient cohorts, GPN3 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,118 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GPN3-associated proteins across cancer lineages are MCM2, MCM3, and TK1. Each is linked with GPN3 in more than 5 cancer types. Because this analysis shows association rather than direction, both GPN3-to-partner and partner-to-GPN3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GPN3 versus MCM2 in HNSC, with a Pearson correlation of 0.31.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GPN3→partner) and Y-score (partner→GPN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MCM2 →	+0.601	+0.579	<.001	.006	3	6
LSCC	MCM3 →	+0.603	+0.535	<.001	<.001	3	6
LUAD	TK1 →	+0.656	+0.458	<.001	<.001	3	5
LSCC	RFC2 →	+0.458	+0.645	<.001	<.001	3	5
LSCC	DCTPP1 →	+0.635	+0.560	<.001	<.001	3	5
UCEC	MED4 →	+0.219	+0.429	<.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,118 associations by consensus.

GPN3 vs MCM2 — HNSC

Explore this scatter interactively →