GPN3

Across TCGA patient cohorts, GPN3 protein abundance is significantly associated with the RNA expression of many other genes, with 5,753 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GPN3-associated genes across cancer lineages are CXCR1, CXCR2, and PLEKHS1. Each is linked with GPN3 in more than 3 cancer types. Because this analysis shows association rather than direction, both GPN3-to-partner and partner-to-GPN3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GPN3 versus CXCR1 in UCEC, with a Pearson correlation of -0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPN3→partner) and Y-score (partner→GPN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CXCR1 →	-0.827	-0.211	<.001	.001	3	4
LSCC	CXCR2 →	-1.299	-0.212	<.001	<.001	3	4
UCEC	PLEKHS1 →	-1.680	-0.236	.001	.001	3	3
LSCC	PPP4R4 →	-1.317	-0.199	<.001	<.001	3	3
GBM	ADGRE3 →	-0.650	-0.416	<.001	<.001	3	3
GBM	CEACAM3 →	-0.500	-0.421	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,753 associations by consensus.

GPN3 vs CXCR1 — UCEC

Explore this scatter interactively →