GPN3

Across TCGA cell cohorts, GPN3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,530 significant associations in total. BONE shows the largest number of these associations.

The most reproducible GPN3-associated GO terms across cancer lineages are DNA replication, Nuclear division, and Kinetochore assembly. Each is linked with GPN3 in more than 17 cancer types. Because this analysis shows association rather than direction, both GPN3-to-partner and partner-to-GPN3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA replication grouped by GPN3-low versus GPN3-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GPN3→partner) and Y-score (partner→GPN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	DNA replication →	+0.142	+1.259	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	Nuclear division →	+0.096	+0.955	.002	.003	3	18
STOMACH	Kinetochore assembly →	+0.098	+0.632	.002	.004	3	17
KIDNEY	Regulation of centrosome duplication →	+0.064	+0.862	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Protein localization to condensed chromosome →	+0.174	+1.049	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Protein localization to kinetochore →	+0.191	+1.135	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,530 associations by consensus.

DNA replication by GPN3 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →