GPN3

Across TCGA cell cohorts, GPN3 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GPN3-associated genes across cancer lineages are ELSPBP1, AADACL3, and OR12D1. Each is linked with GPN3 in more than 1 cancer types. Because this analysis shows association rather than direction, both GPN3-to-partner and partner-to-GPN3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ELSPBP1 grouped by GPN3-low versus GPN3-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPN3→partner) and Y-score (partner→GPN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	ELSPBP1 →	+0.075	+5.539	<.001	.003	3	1
BLOOD_Leukemia	AADACL3 →	+0.012	+4.922	<.001	.009	3	1
BLOOD_Leukemia	OR12D1 →	+0.006	+5.969	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

ELSPBP1 by GPN3 expression — BLOOD_Leukemia

Explore this box plot interactively →