GPM6B

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GPM6B protein abundance is significantly associated with the RNA expression of many other genes, with 6,565 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GPM6B-associated genes across cancer lineages are SEPTIN3, KIAA0930, and BEX4. Each is linked with GPM6B in more than 1 cancer types. Because this analysis shows association rather than direction, both GPM6B-to-partner and partner-to-GPM6B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GPM6B versus SEPTIN3 in GBM, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPM6B→partner) and Y-score (partner→GPM6B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMSEPTIN3 →+1.293+0.617<.001<.00132
COADKIAA0930 →+0.493+0.449<.001<.00132
COADBEX4 →+1.035+0.632<.001<.00132
GBMNCS1 →+0.826+0.594<.001<.00132
GBMPTGDS →+1.160+0.407.003.00832
GBMPPP3CB →+0.377+0.414.004.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 6,565 associations by consensus.

GPM6B vs SEPTIN3 — GBM

Per-sample scatter of GPM6B vs SEPTIN3 in GBM (Pearson r = 0.37).

Explore this scatter interactively →

Exploration