GPM6B

Across TCGA cell cohorts, GPM6B RNA expression is significantly associated with the go_rna of many other GO terms, with 5,357 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible GPM6B-associated GO terms across cancer lineages are Negative regulation of gene expression, epigenetic, Positive regulation of DNA metabolic process, and Epigenetic regulation of gene expression. Each is linked with GPM6B in more than 11 cancer types. Because this analysis shows association rather than direction, both GPM6B-to-partner and partner-to-GPM6B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of gene expression, epigenetic grouped by GPM6B-low versus GPM6B-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GPM6B→partner) and Y-score (partner→GPM6B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Negative regulation of gene expression, epigenetic →	+0.073	+1.062	<.001	.004	3	12
LUNG_SCLC	Positive regulation of DNA metabolic process →	+0.077	+2.159	<.001	<.001	3	12
LUNG_SCLC	Epigenetic regulation of gene expression →	+0.069	+2.087	<.001	<.001	3	12
LUNG_SCLC	Positive regulation of DNA recombination →	+0.093	+2.013	<.001	<.001	3	12
SOFT_TISSUE	Regulation of body fluid levels →	-0.116	-3.611	<.001	<.001	3	12
LUNG_SCLC	Regulation of microtubule-based process →	+0.066	+1.737	<.001	.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,357 associations by consensus.

Negative regulation of gene expression, epigenetic by GPM6B expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →