GPM6A

Across TCGA patient cohorts, GPM6A protein abundance is significantly associated with the protein abundance of many other proteins, with 17,784 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GPM6A-associated proteins across cancer lineages are CA4, ADD1, and ADD1_S12. Each is linked with GPM6A in more than 2 cancer types. Because this analysis shows association rather than direction, both GPM6A-to-partner and partner-to-GPM6A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GPM6A versus CA4 in GBM, with a Pearson correlation of 0.63.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GPM6A→partner) and Y-score (partner→GPM6A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CA4 →	+0.883	+0.738	<.001	<.001	3	3
GBM	ADD1 →	+0.377	+0.789	<.001	<.001	3	3
LUAD	ADD1_S12 →	+0.466	+0.754	.001	<.001	3	3
GBM	CCDC85A_S255 →	+1.019	+0.977	<.001	<.001	3	3
LUAD	CLDN5_T207 →	+1.316	+0.864	<.001	<.001	3	3
GBM	CNRIP1 →	+0.697	+0.895	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,784 associations by consensus.

GPM6A vs CA4 — GBM

Explore this scatter interactively →