GPM6A

Across TCGA cell cohorts, GPM6A RNA expression is significantly associated with the go_rna of many other GO terms, with 2,024 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible GPM6A-associated GO terms across cancer lineages are Potassium ion transport, Adenylate cyclase-modulating G protein-coupled receptor signaling pathway, and Adenylate cyclase-activating G protein-coupled receptor signaling pathway. Each is linked with GPM6A in more than 7 cancer types. Because this analysis shows association rather than direction, both GPM6A-to-partner and partner-to-GPM6A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Potassium ion transport grouped by GPM6A-low versus GPM6A-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GPM6A→partner) and Y-score (partner→GPM6A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Potassium ion transport →	-0.060	-0.398	<.001	.003	3	8
PANCREAS	Adenylate cyclase-modulating G protein-coupled receptor signaling pathway →	-0.046	-0.539	<.001	<.001	3	7
PANCREAS	Adenylate cyclase-activating G protein-coupled receptor signaling pathway →	-0.046	-0.673	<.001	<.001	3	7
UPPER_AERODIGESTIVE_TRACT	T-helper 17 cell differentiation →	+0.165	+0.697	<.001	.005	3	7
BREAST	Potassium ion transmembrane transport →	-0.056	-0.366	.001	.008	3	6
BREAST	Regulation of postsynaptic membrane potential →	-0.069	-0.290	<.001	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,024 associations by consensus.

Potassium ion transport by GPM6A expression — BREAST

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