GPHN

Across TCGA patient cohorts, GPHN RNA expression is significantly associated with the protein abundance of many other proteins, with 20,303 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GPHN-associated proteins across cancer lineages are GPHN_S305, MTA1, and PPP4R3A. Each is linked with GPHN in more than 8 cancer types. Because this analysis shows association rather than direction, both GPHN-to-partner and partner-to-GPHN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GPHN versus GPHN_S305 in BRCA, with a Pearson correlation of 0.60.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GPHN→partner) and Y-score (partner→GPHN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	GPHN_S305 →	+0.980	+0.779	<.001	<.001	3	9
GBM	MTA1 →	+0.411	+0.673	<.001	<.001	3	7
GBM	PPP4R3A →	+0.389	+0.746	<.001	<.001	3	7
HNSC	UBR7 →	+0.423	+0.933	<.001	<.001	3	7
GBM	RRBP1 →	-0.429	-0.704	.001	<.001	3	6
GBM	BAG5 →	+0.351	+0.653	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,303 associations by consensus.

GPHN vs GPHN_S305 — BRCA

Explore this scatter interactively →