GPHN

Across TCGA cell cohorts, GPHN RNA expression is significantly associated with the go_rna of many other GO terms, with 3,931 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible GPHN-associated GO terms across cancer lineages are Gamma-aminobutyric acid receptor clustering, Antigen processing and presentation of peptide antigen, and Mo-molybdopterin cofactor metabolic process. Each is linked with GPHN in more than 19 cancer types. Because this analysis shows association rather than direction, both GPHN-to-partner and partner-to-GPHN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Gamma-aminobutyric acid receptor clustering grouped by GPHN-low versus GPHN-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GPHN→partner) and Y-score (partner→GPHN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Gamma-aminobutyric acid receptor clustering →	+1.941	+3.266	<.001	<.001	3	20
LUNG_SCLC	Antigen processing and presentation of peptide antigen →	-0.125	-0.988	<.001	<.001	3	11
BREAST	Mo-molybdopterin cofactor metabolic process →	+0.150	+1.040	.001	.006	3	11
BREAST	Molybdopterin cofactor biosynthetic process →	+0.150	+1.040	.001	.006	3	11
BREAST	Molybdopterin cofactor metabolic process →	+0.150	+1.040	.001	.006	3	11
BREAST	Prosthetic group metabolic process →	+0.150	+1.040	.001	.006	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,931 associations by consensus.

Gamma-aminobutyric acid receptor clustering by GPHN expression — BLOOD_Lymphoma

Explore this box plot interactively →