GPHA2

Across TCGA cell cohorts, GPHA2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,603 significant associations in total. BONE shows the largest number of these associations.

The most reproducible GPHA2-associated GO terms across cancer lineages are Nuclear-transcribed mRNA catabolic process, non-stop decay, Response to calcium ion, and Chromosome localization to nuclear envelope involved in homologous chromosome segregation. Each is linked with GPHA2 in more than 5 cancer types. Because this analysis shows association rather than direction, both GPHA2-to-partner and partner-to-GPHA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear-transcribed mRNA catabolic process, non-stop decay grouped by GPHA2-low versus GPHA2-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GPHA2→partner) and Y-score (partner→GPHA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Nuclear-transcribed mRNA catabolic process, non-stop decay →	+0.045	+0.140	.003	.008	3	6
BONE	Response to calcium ion →	-0.160	-0.779	<.001	<.001	3	6
LUNG_NSCLC_LUAD	Chromosome localization to nuclear envelope involved in homologous chromosome segregation →	-0.231	-0.249	<.001	<.001	3	5
LUNG_SCLC	Regulation of ossification →	-0.056	-0.340	.001	<.001	3	5
BONE	Regulation of sodium ion export across plasma membrane →	-0.285	-0.459	<.001	.006	3	5
BONE	Positive regulation of sodium ion export across plasma membrane →	-0.285	-0.459	<.001	.006	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,603 associations by consensus.

Nuclear-transcribed mRNA catabolic process, non-stop decay by GPHA2 expression — LARGE_INTESTINE

Explore this box plot interactively →