GPD1L

Across TCGA patient cohorts, GPD1L mutation is significantly associated with the RNA expression of many other genes, with 3,439 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GPD1L-associated genes across cancer lineages are RNA5SP72, TRAJ57, and RNA5SP369. Each is linked with GPD1L in more than 1 cancer types. Because this analysis shows association rather than direction, both GPD1L-to-partner and partner-to-GPD1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP72 grouped by GPD1L-low versus GPD1L-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPD1L→partner) and Y-score (partner→GPD1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP72 →	+0.241	+2.353	<.001	.004	3	2
UCEC	TRAJ57 →	+0.379	+1.997	<.001	.007	3	2
UCEC	RNA5SP369 →	+0.383	+2.193	<.001	.002	3	2
BLCA	MFSD4BP1 →	+0.059	+4.642	<.001	.004	3	2
STAD	H2BL1P →	+0.207	+4.290	.006	.008	3	2
UCEC	BTBD10 →	+0.561	+3.732	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,439 associations by consensus.

RNA5SP72 by GPD1L expression — UCEC

Explore this box plot interactively →