GPD1

Across TCGA patient cohorts, GPD1 mutation is significantly associated with the RNA expression of many other genes, with 2,070 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GPD1-associated genes across cancer lineages are RNA5SP419, MEX3D, and BTBD6. Each is linked with GPD1 in more than 2 cancer types. Because this analysis shows association rather than direction, both GPD1-to-partner and partner-to-GPD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP419 grouped by GPD1-low versus GPD1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPD1→partner) and Y-score (partner→GPD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP419 →	+0.481	+1.796	<.001	.008	3	3
UCEC	MEX3D →	+0.717	+3.021	<.001	<.001	3	2
UCEC	BTBD6 →	+0.364	+1.947	.002	.003	3	2
UCEC	UBE2L3 →	+0.363	+3.774	<.001	<.001	3	2
UCEC	CIDECP1 →	+0.513	+2.992	<.001	<.001	3	2
UCEC	ZNF25-DT →	+0.107	+1.764	.004	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,070 associations by consensus.

RNA5SP419 by GPD1 expression — UCEC

Explore this box plot interactively →