GPCPD1

Across TCGA patient cohorts, GPCPD1 mutation is significantly associated with the RNA expression of many other genes, with 1,804 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GPCPD1-associated genes across cancer lineages are RN7SL248P, FAM177A1, and ANXA5. Each is linked with GPCPD1 in more than 2 cancer types. Because this analysis shows association rather than direction, both GPCPD1-to-partner and partner-to-GPCPD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL248P grouped by GPCPD1-low versus GPCPD1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPCPD1→partner) and Y-score (partner→GPCPD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL248P →	+0.068	+3.330	<.001	<.001	3	3
UCEC	FAM177A1 →	+0.385	+2.839	<.001	.001	3	2
UCEC	ANXA5 →	+0.435	+2.010	.002	.001	3	2
UCEC	NPPA →	+0.266	+1.727	.003	.006	3	2
UCEC	GLRX2 →	+0.410	+2.010	.009	.001	3	2
UCEC	TRPM7 →	+0.424	+2.000	.006	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,804 associations by consensus.

RN7SL248P by GPCPD1 expression — UCEC

Explore this box plot interactively →