Across TCGA patient cohorts, GPC6 RNA expression is significantly associated with the RNA expression of many other genes, with 17,813 significant associations in total. UVM shows the largest number of these associations.

The most reproducible GPC6-associated genes across cancer lineages are NID2, RAI14, and PTPRG. Each is linked with GPC6 in more than 29 cancer types. Because this analysis shows association rather than direction, both GPC6-to-partner and partner-to-GPC6 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPC6→partner) and Y-score (partner→GPC6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
TGCT	NID2 →	+1.868	+1.970	<.001	<.001	3	30
THYM	RAI14 →	+1.170	+1.374	<.001	<.001	3	30
MESO	PTPRG →	+1.096	+1.354	<.001	<.001	3	29
UVM	RECQL →	+1.479	+0.321	<.001	<.001	3	29
UVM	PPFIBP1 →	+1.478	+0.456	<.001	<.001	3	29
UVM	AP3B1 →	+0.949	+0.308	<.001	<.001	3	29

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,813 associations by consensus.

Exploration

GPC6 survival (RNA) · tumor vs normal (RNA) · all GPC6 data types