GPC5-AS2

Across TCGA pan-cancer cohorts, GPC5-AS2 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of GPC5-AS2’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where GPC5-AS2 RNA is repressed in tumor relative to normal tissue. In most cancer types GPC5-AS2 is over-expressed in tumor, although a few such as LUSC show the opposite, repressed pattern.

LUSC are the cancer types where GPC5-AS2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in GPC5-AS2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	Female	III,IV	−0.235	.004	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 1 strongest of 1 lineages.

GPC5-AS2–LUSC

Open the LUSC breakdown →