GPBAR1

Across TCGA patient cohorts, GPBAR1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,689 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GPBAR1-associated proteins across cancer lineages are TLN1, GIMAP7, and NFATC2. Each is linked with GPBAR1 in more than 6 cancer types. Because this analysis shows association rather than direction, both GPBAR1-to-partner and partner-to-GPBAR1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GPBAR1 versus TLN1 in COAD, with a Pearson correlation of 0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GPBAR1→partner) and Y-score (partner→GPBAR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	TLN1 →	+0.468	+0.613	<.001	<.001	3	7
LSCC	GIMAP7 →	+0.770	+0.336	<.001	<.001	3	6
LSCC	NFATC2 →	+0.367	+0.282	<.001	<.001	3	6
BRCA	CAVIN1 →	+0.853	+0.352	<.001	.001	3	6
PDAC	CLIC2 →	+0.429	+0.784	<.001	<.001	3	6
GBM	DAB2 →	+0.512	+0.193	.002	.004	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,689 associations by consensus.

GPBAR1 vs TLN1 — COAD

Explore this scatter interactively →