Across TCGA patient cohorts, GPATCH8 RNA expression is significantly associated with the protein abundance of many other proteins, with 20,096 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GPATCH8-associated proteins across cancer lineages are SF3B3, MAN2A1, and VEZF1. Each is linked with GPATCH8 in more than 5 cancer types. Because this analysis shows association rather than direction, both GPATCH8-to-partner and partner-to-GPATCH8 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GPATCH8→partner) and Y-score (partner→GPATCH8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SF3B3 →	+0.286	+0.431	<.001	<.001	3	6
GBM	MAN2A1 →	-0.467	-0.403	<.001	<.001	3	6
GBM	VEZF1 →	+0.451	+0.326	<.001	<.001	3	6
GBM	ZNF830 →	+0.410	+0.458	<.001	<.001	3	5
OV	RPL26 →	-0.503	-0.880	<.001	.001	3	5
GBM	SMARCC2 →	+0.397	+0.493	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,096 associations by consensus.

Exploration

GPATCH8 survival (RNA) · tumor vs normal (RNA) · all GPATCH8 data types