Across TCGA patient cohorts, GPATCH8 mutation is significantly associated with the total protein of many other genes, with 68 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GPATCH8-associated genes across cancer lineages are CD20, Caspase-7-cleavedD198, and eEF2. Each is linked with GPATCH8 in more than 3 cancer types. Because this analysis shows association rather than direction, both GPATCH8-to-partner and partner-to-GPATCH8 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPATCH8→partner) and Y-score (partner→GPATCH8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CD20 →	+0.102	+1.341	.004	.006	3	3
STAD	Caspase-7-cleavedD198 →	+0.888	+3.000	.020	.036	2	4
UCEC	eEF2 →	+0.335	+2.415	<.001	.002	3	3
UCEC	PKC-b-II_pS660 →	-0.166	-1.201	.028	.025	3	3
UCEC	c-Met_pY1235 →	+0.050	+1.050	.014	.023	3	3
COAD	Cyclin-E2 →	+0.263	+3.008	.028	.019	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 68 associations by consensus.

Exploration

GPATCH8 survival (RNA) · tumor vs normal (RNA) · all GPATCH8 data types