Across TCGA cell cohorts, GPATCH8 mutation is significantly associated with the RNA expression of many other genes, with 1,208 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GPATCH8-associated genes across cancer lineages are CABP5, SLC38A8, and OR56A1. Each is linked with GPATCH8 in more than 2 cancer types. Because this analysis shows association rather than direction, both GPATCH8-to-partner and partner-to-GPATCH8 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPATCH8→partner) and Y-score (partner→GPATCH8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	CABP5 →	+0.009	+3.867	<.001	.002	3	2
BLOOD_Lymphoma	SLC38A8 →	+0.075	+3.606	<.001	.002	3	2
BLOOD_Lymphoma	OR56A1 →	+0.031	+3.938	<.001	.001	3	2
BLOOD_Lymphoma	OR56A3 →	+0.529	+3.938	<.001	.001	3	2
BLOOD_Leukemia	GRK3 →	+1.484	+3.199	<.001	.007	3	2
BLOOD_Leukemia	SEC24A →	+0.580	+3.199	.003	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,208 associations by consensus.

Exploration

GPATCH8 survival (RNA) · tumor vs normal (RNA) · all GPATCH8 data types