Across TCGA patient cohorts, GPATCH3 mutation is significantly associated with the RNA expression of many other genes, with 2,185 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GPATCH3-associated genes across cancer lineages are RN7SL393P, RNA5SP433, and RNU6-38P. Each is linked with GPATCH3 in more than 2 cancer types. Because this analysis shows association rather than direction, both GPATCH3-to-partner and partner-to-GPATCH3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPATCH3→partner) and Y-score (partner→GPATCH3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RN7SL393P →	+0.865	+6.392	<.001	.001	3	3
HNSC	RNA5SP433 →	+0.587	+5.736	<.001	.003	3	2
HNSC	RNU6-38P →	+0.394	+6.763	<.001	<.001	3	2
HNSC	RNU6-1104P →	+0.497	+6.468	<.001	.001	3	2
HNSC	MIR301B →	+0.467	+5.241	<.001	.007	3	2
HNSC	WASHC3P1 →	+0.391	+5.822	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,185 associations by consensus.

Exploration

GPATCH3 survival (RNA) · tumor vs normal (RNA) · all GPATCH3 data types