GPATCH11

Across TCGA cell cohorts, GPATCH11 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GPATCH11-associated genes across cancer lineages are TRARG1 and KLF18. Each is linked with GPATCH11 in more than 1 cancer types. Because this analysis shows association rather than direction, both GPATCH11-to-partner and partner-to-GPATCH11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRARG1 grouped by GPATCH11-low versus GPATCH11-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPATCH11→partner) and Y-score (partner→GPATCH11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TRARG1 →	+0.027	+3.930	<.001	.003	3	1
LARGE_INTESTINE	KLF18 →	+0.009	+3.930	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

TRARG1 by GPATCH11 expression — LARGE_INTESTINE

Explore this box plot interactively →