GPAT4

Across TCGA patient cohorts, GPAT4 protein abundance is significantly associated with the RNA expression of many other genes, with 6,144 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible GPAT4-associated genes across cancer lineages are GOLGA7, GINS4, and POLB. Each is linked with GPAT4 in more than 5 cancer types. Because this analysis shows association rather than direction, both GPAT4-to-partner and partner-to-GPAT4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GPAT4 versus GOLGA7 in LSCC, with a Pearson correlation of 0.64.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPAT4→partner) and Y-score (partner→GPAT4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	GOLGA7 →	+0.584	+0.375	<.001	<.001	3	6
LUAD	GINS4 →	+0.931	+0.534	<.001	<.001	3	5
OV	POLB →	+0.745	+0.471	<.001	.001	3	5
HNSC	BRF2 →	+0.734	+0.354	.004	.001	2	5
BRCA	FNTA →	+0.595	+0.525	<.001	<.001	3	4
OV	LSM1 →	+0.688	+0.392	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,144 associations by consensus.

GPAT4 vs GOLGA7 — LSCC

Explore this scatter interactively →