GPAT4

Across TCGA cell cohorts, GPAT4 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,034 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible GPAT4-associated GO terms across cancer lineages are Negative regulation of calcium ion export across plasma membrane, Peptidyl-serine phosphorylation, and Peptidyl-serine modification. Each is linked with GPAT4 in more than 14 cancer types. Because this analysis shows association rather than direction, both GPAT4-to-partner and partner-to-GPAT4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of calcium ion export across plasma membrane grouped by GPAT4-low versus GPAT4-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GPAT4→partner) and Y-score (partner→GPAT4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Negative regulation of calcium ion export across plasma membrane →	+0.095	+1.163	<.001	.001	3	15
UPPER_AERODIGESTIVE_TRACT	Peptidyl-serine phosphorylation →	+0.070	+1.494	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Peptidyl-serine modification →	+0.070	+1.474	<.001	<.001	3	14
LARGE_INTESTINE	RISC complex assembly →	+0.098	+0.967	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Vacuole organization →	+0.044	+0.894	<.001	<.001	3	13
LARGE_INTESTINE	Microtubule polymerization →	+0.132	+0.888	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,034 associations by consensus.

Negative regulation of calcium ion export across plasma membrane by GPAT4 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →