GPAT2P1

Across TCGA patient cohorts, GPAT2P1 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible GPAT2P1-associated genes across cancer lineages are FAM41AY2, PRAMEF32P, and RNU7-7P. Each is linked with GPAT2P1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GPAT2P1-to-partner and partner-to-GPAT2P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM41AY2 grouped by GPAT2P1-low versus GPAT2P1-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPAT2P1→partner) and Y-score (partner→GPAT2P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	FAM41AY2 →	+0.064	+7.954	<.001	.008	3	1
HNSC	PRAMEF32P →	+0.029	+7.954	<.001	.008	3	1
HNSC	RNU7-7P →	+0.377	+7.954	<.001	.008	3	1
HNSC	RNA5SP461 →	+0.247	+7.954	<.001	.008	3	1
HNSC	BNIP3P6 →	+0.059	+7.954	<.001	.008	3	1
HNSC	MIR548AG1 →	+0.447	+7.954	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

FAM41AY2 by GPAT2P1 expression — HNSC

Explore this box plot interactively →